When you see a medical emergency in a crowd, experts advise that you select a bystander and clearly direct them to call 911. Surprisingly, when a virus invades the body, our cells may follow similar …
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The Institute for Molecular Virology Hosts the 2nd Annual Palmenberg Symposium
On March 26, 2026, the Institute for Molecular Virology (IMV) hosted the 2nd Annual Ann Palmenberg Molecular Virology Symposium. Sponsored by the Wisconsin Alumni Research Foundation, the Department of Biochemistry, and generous gifts from alumni …
In just 17 amino acids, a master regulator of viral genome replication
Positive-strand RNA viruses comprise a vast and often fearsome roster that includes poliovirus, hepatitis C, dengue, Zika, HIV, SARS-CoV-2, and many agriculturally important plant viruses. But it’s the small things — the molecular machines fueling …
Throwing Sand in the Gears of Viral Replication
When viruses infect cells, they act like well-oiled machines, hijacking cellular resources and cranking out countless copies of their genetic material to help spread the infection. A new study published in the Journal of Biological …
Gaglia Lab Featured in UW-Health Advances for Cutting-Edge Research on Major Cancer Viruses
Most people infected with human herpesvirus 8, also called Kaposi’s sarcoma-associated herpesvirus, likely will not have any health issues or symptoms from it. The virus is not curable, but it stays dormant in people with …
Identifying Ways HIV Tricks Cells into Making More Virus
University of Wisconsin-Madison scientists at the Institute of Molecular Virology have uncovered a clever strategy that HIV-1 uses to squeeze more viral particles out of every cell it infects. A recent research paper published in …
Hepatitis B virus strains the cell’s DNA repair defenses
Cancer and diseases associated with hepatitis B virus (HBV) infection kill over 800,000 people every year. Antiviral therapies are rarely able to cure patients of HBV infection. To try to answer why, researchers at the University of Wisconsin – Madison’s Institute of Molecular Virology are investigating where and how the virus persists in human cells.